Vancomycin Initial Dosing

Calculate the initial loading and maintenance dose for intravenous Vancomycin based on actual body weight and renal function (CrCl).

Calculate using Cockcroft-Gault.

Initial Regimen

Loading Dose (Based on actual weight)

mg (IV)

*Max loading dose typically 2500mg-3000mg depending on local policy. Infuse over at least mins to avoid red man syndrome.

Maintenance Dose (Based on CrCl)

mg every hours

Guidelines (General)

  • Loading Dose: 25-30 mg/kg (actual body weight).
  • Maintenance: 15-20 mg/kg/dose.
  • CrCl > 90: q8h or q12h.
  • CrCl 50-90: q12h.
  • CrCl 20-49: q24h.
  • CrCl < 20: Dose by levels (pulse dosing).

Disclaimer: Vancomycin protocols are highly localized. Always default to your Trust's specific MicroGuide/formulary policy.

← Back to all tools